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Senior Protein Engineer Scientist

Vertex

Seattle, Washington, United States Full time July 20, 2026
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Vacancy Description

Job Description

General Summary:

Our Seattle site is seeking a talented and motivated Protein Engineer (Senior Scientist) to join our dynamic team. If you are passionate about advancing scientific research and developing novel therapeutics, this role is for you!

Key Duties and Responsibilities:

  • Design and execute protein engineering/directed evolution campaigns to improve binding affinity, stability, and selectivity.
  • Utilize yeast surface display technology for library screening and directed evolution.
  • Drawing from a deep array of Rosetta scripts and machine learning tools, create computational design strategies to deliver protein drug candidates.
  • Effectively communicate design strategies to interdisciplinary team members.
  • Collaborate with cross-functional teams to optimize protein candidates for function, manufacturability, and immunogenicity.
  • Prepare reports...

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