Role
To conduct research under the supervision of senior colleagues and to contribute to the production of research, in particular to:
Engineer enzymes to confer novel functionalitiesAssay enzyme activity using LC-MS/HPLC and biochemical assaysDetermine the chemical mechanisms underlying enzyme activityDetermine enzyme structures using X-ray crystallographyAnalyse biological samples using TEM and SEM Skills, Experience & Qualification needed
Undergraduate degree in ChemistryPhD in enzyme engineering, structural biology, biocatalysis and equivalent experienceKnowledge of protein-ligand complex structure determination by X-ray crystallographyKnowledge in enzyme engineering including mutant library constructionKnowledge in enzyme assaying by LC-MS and HPLCSkills in generating structure- and AI-guided mutant librar...