Principal Scientist, Early Pipeline Development

Job Description Summary

We are seeking a highly motivated Principal Scientist I with extensive AAV gene therapy manufacturing experience to develop state‑of‑the‑art downstream purification processes for next‑generation AAV gene therapy. This role is also responsible for executing early‑stage process development with the focus on developability of AAV gene therapy lead candidates as well as new platform process development for existing and novel AAV capsids and cargo vectors.

Job Description

Internal Job Title: Principal Scientist I/II

Position Location: Onsite, San Diego, CA

Key Responsibilities

• Lead and manage a 3‑5 person downstream process team and provide technical support, training, and SME knowledge to assist with the professional development of direct reports.
• Coordinate activities with associates across upstream process and analytical teams.
• ...