Vacancy Description
Location: Vestal, NY Category: Professional & Support Staff Job Type: Full-time Posted On: Fri Jul 24 2026 Job Description:
The Postdoctoral Research Associate will be responsible for achieving the Specific Aims of the NIGMS R35 GM130207 project titled Chemical Approaches to Control the Function of Regulatory RNAs. The project focuses on synthesis, biophysical studies, and biological (cell culture) experiments to test whether backbone-modified nucleic acid analogues can modulate the structure and function of biologically relevant RNAs. Specifically, the Postdoctoral Research Associate will:
+ Develop synthetic methods to prepare backbone-modified RNA and peptide nucleic acids (PNAs). This will be done using techniques of synthetic organic chemistry and by adopting and optimizing solid-phase peptide, PNA, and RNA synthesis methods;
+ Synthesize small interfering RNAs with various backbone modifications using an automated RNA synthesizer and the monomer...
The Postdoctoral Research Associate will be responsible for achieving the Specific Aims of the NIGMS R35 GM130207 project titled Chemical Approaches to Control the Function of Regulatory RNAs. The project focuses on synthesis, biophysical studies, and biological (cell culture) experiments to test whether backbone-modified nucleic acid analogues can modulate the structure and function of biologically relevant RNAs. Specifically, the Postdoctoral Research Associate will:
+ Develop synthetic methods to prepare backbone-modified RNA and peptide nucleic acids (PNAs). This will be done using techniques of synthetic organic chemistry and by adopting and optimizing solid-phase peptide, PNA, and RNA synthesis methods;
+ Synthesize small interfering RNAs with various backbone modifications using an automated RNA synthesizer and the monomer...
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